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Neurology Risk Panel
Dementia affects over 50 million people globally, with 25% of individuals aged 55 and above having a family history linked to this condition. Neurology genetic testing involves analyzing an individual's genetic makeup to identify specific genetic variations associated with neurological disorders or conditions that affect the brain, spinal cord, and nerves. This specialized testing aims to uncover genetic mutations or markers linked to various neurological diseases such as Alzheimer's, Parkinson's, Huntington's disease, and many rare genetic neurodegenerative disease.
Conditions and Genes
Comprehensive overview of specific gene mutations and their respective associations with neurological conditions. This resource provides detailed insights into the intricate relationship between genetic factors and the development of various neurological disorders.
Conditions | Genes |
|---|---|
Ataxia | AKT1, APTX, ANO3, APOE, APP, ATM, ATP1A3, BIN1, CD2AP, CLU, DNMT1, GCH1, GRN, HNRNPA1, HNRNPA2B1, HTRA2, LMNB1, MAPT, NEFH, OPTN, PARK7, PRNP, PSEN1, PTK2B, SNCA, SOD1, SQSTM1, TOR1A, TP53, TUBA4A |
Multiple sclerosis | TP53, APOE, CLCN6, POLG, SOD1, SPAST, PRNP, SETX, MAPT, ATM, CLU, PICALM, CR1, ABCA7, TREM2, PVRL2, PRKRA, NEFH, EPHA4, FIG4, UNC13A, LMNB1, DCTN1, VAPB, ALS2, BTNL2, TYROBP |
Parkinson's Disease | AKT1,ADORA1, ARDBP, ATP1A3, ATP6AP2, ANG, APOE, APP, ATP13A2, ARDBP, CHCHD2, CHCHD10, CHMP2B, CLU, CR1, DNAJC6, EIF4G1, FBXO7, FUS, GAK, GBA, GCH1, GIGYF2, GRN, HTRA2, LRRK2, MAPT, MEF2C, PARK2, PARK7, PFN1, PICALM, PINK1, PRRT2, PLA2G6, PTK2B, SARM1, POLG, RAB39B, RAB7L1, SCARB2, SNCA, SOD1, RAB38, SYNJ1, TAF1, TBK1, TBP, TMEM230, TOMM40, TP53, TREM2, VCP, VPS13C, VPS35 |
Huntington's Disease | AKT1, ATM, PARK7, PRNP, RIN3, SOD1, TBP, TP53 |
Alzheimer's Disease | ABCA7, ABI3, ADAM10, AKT1, ANG, APOE, APP, BIN1, CASS4, CD2AP, CD33, CELF1, CLU, CTSC, CSF1R, CR1, EPHA1, ELAVL1, FERMT2, GBA, GRN, HNRNPA1, INPP5D, ITM2B, LRRK2, MAPT, MARK2, MARK4, MS4A4A, MS4A6E, NEFH, NME8, NEK1, NOTCH3, PARK7, PTK2B, PICALM, PLCG2, POLG,PFN1, PRNP, PSEN1, PSEN2, SLC24A4, SNCA, SOD1, SORL1, SQSTM1,UBQLN2, TMEM106B, TOMM40, TP53, TRIP4, TREM2, ZCWPW1 |
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